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Adryl Syrup

Original price was: ৳ 45.00.Current price is: ৳ 42.75.

Description

Pharmacology
Diphenhydramine has anti-histaminic (H1-receptor), anti-emetic, anti-vertigo and sedative and hypnotic properties. The anti-histamine action occurs by blocking the spasmogenic and congestive effects of histamine by competing with histamine for H1 receptor sites on effector cells, preventing but not reversing responses mediated by histamine alone. Such receptor sites may be found in the gut, uterus, large blood vessels, bronchial muscles, and elsewhere. Anti-emetic action is by inhibition at the medullary chemoreceptor trigger zone. Anti-vertigo action is by a central antimuscarinic effect on the vestibular apparatus and the integrative vomiting center and medullary chemoreceptor trigger zone of the midbrain.

Indication:
For the treatment of following: 1) Seasonal, perennial & vasomotor rhinitis, 2) urticaria, angioneurotic edema, anaphylaxis, 3) pruritus, 4) preanesthetic medication, emesis, motion sickness, 5) miscellaneous including meniere’s diseases and parkinsonism, 6) cough & cold. Sometimes it may use as a night time sleep aid and for the short-term management of insomnia.

Dosage & Administration:
Most allergic conditions are controlled with 25 to 50 mg i.e., (12.5 to 25 ml of syrup) 3 to 4 times a day.
Children 6 to 12 years of age : 10 mg i.e., (5 ml of syrup) 3 to 4 times a day.
Children 1 to 6 years of age: 5 mg i.e., (2.5 ml of syrup) 3 to 4 times a day.
In motion sickness: Adult : 25 to 50 mg 3 to 4 times a day. Children (above 9.1 kg): 12.5 to 25 mg 3 to 4 times a day (5mg/ kg/ 24 hours).
In parkinsonism: Adult : 25 to 50 mg 3 to 4 times a day. Children (above 9.1 kg) : 12.5 to 25 mg 3 to 4 times a day (5mg/ kg/ 24 hours).
In insomnia: Adults and children over 12 years of old : A dose of 20 to 50 mg is used as hypnotic in insomnia.
In cough & cold: Adults : 25 mg every 4 hrs. Not to exceed 150 mg in 24 hours. Children (6 to 12 years) : 12.5 mg every 4 hours. Not to exceed 75 mg in 24 hours. Children (2 to 6 years) : 6.25 mg every 4 hours.

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